008 Demonstration of cardiac AL amyloidosis regression after succesful chemotherapy. a CMR study
نویسندگان
چکیده
منابع مشابه
CMR-based characterization of cardiac amyloidosis.
Amyloidosis is a systemic disease caused by the deposition of misfolded proteins. Cardiac involvement is a major cause of morbidity and mortality, especially in the light chain (AL) and transthyretin (ATTR) forms. Amyloidosis usually presents as a restrictive cardiomyopathy with progressive systolic/ diastolic dysfunction and arrhythmias but is often misdiagnosed as hypertrophic or hypertensive...
متن کاملReply: CMR-Based Characterization of Cardiac Amyloidosis.
We thank Barison et al. for their interest in our paper (1). Cardiac amyloidosis is gaining significant exposure in the cardiac magnetic resonance (CMR) community because of the characteristic and near pathognomonic findings with the technique. We reported the first study that specifically aimed to differentiate between the light chain (AL) and transthyretin (ATTR) subtypes of amyloidosis throu...
متن کاملNative T1 mapping in ATTR cardiac amyloidosis - comparison with AL cardiac amyloidosis - a 200 patient study
Background Transthyretin amyloidosis (ATTR amyloidosis) is an under diagnosed cause of heart failure with no truly quantitative test. Cardiac involvement is the leading cause of death and influences therapeutic choices. Since new therapies are imminent which aim to treat ATTR amyloidosis the lack of a quantitative test represents a critical step for drug development. In cardiac AL amyloidosis, ...
متن کاملRegression of cardiac amyloidosis following stem cell transplantation: a comparison between echocardiography and cardiac magnetic resonance imaging in long-term survivors
BACKGROUND AL amyloidosis and multiple myeloma result in extracellular deposition of insoluble fibrillary protein in tissue and organs. Untreated median survival is very poor, and even worse with cardiac involvement. Chemotherapy and peripheral blood stem cell transplantation (PBSCT) have been shown to dramatically improve survival, with hematologic remission documented. Regression of cardiac c...
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Daubert JP, Eldar M, Gold MR, Goldberger JJ, Goldenberg I, Lichstein E, Pitschner H, Rashtian M, Solomon S, Viskin S, Wang P, Moss AJ. Effectiveness of cardiac resynchronization therapy by QRS morphology in the Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy (MADIT-CRT). Circulation 2011;123:1061–1072. 14. Fang F, Chan JY, Yip GW, Xie JM, Zhang Q, Fung J...
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ژورنال
عنوان ژورنال: Heart
سال: 2017
ISSN: 1355-6037,1468-201X
DOI: 10.1136/heartjnl-2017-311399.8